Phenibut: review of uses, dosage, and side effects

Curious about Phenibut?

Do you wonder about the benefits of Phenibut for regulating mood and anxiety?

Then you’ve come to the right place! Whether you’re considering using Phenibut for anxiety relief or simply want to learn more about this popular nootropic, we’ve got you covered.

In this comprehensive review, we will cover everything you MUST know about Phenibut, including its uses, dosage recommendations, and potential side effects. We also dive into the science behind Phenibut, how it works in the body, and the most effective ways to use it.

We even answer your most important questions, including:

Is Phenibut safe to use long-term?
What is the maximum daily dose for Phenibut?
What are the potential side effects of Phenibut?

By the end of this review, you’ll have all the information you need to make an informed decision on Phenibut and its powerful nootropic.

So, let’s get started!

P.S: Order Phenibut here from a world-class vendor!

(Phenibut.com, sponsored) Phenibut is one of the most popular and powerful nootropics available today.

What is Phenibut?

Phenibut is one of the most popular and powerful nootropics available today.

Phenibut was first researched and developed in the Soviet Union in the 1960s. It was originally studied for its anxiolytic and antidepressant effects in humans, but it has since been used for a variety of purposes, including:

Decreasing social anxiety and potentially improving socialization skills [1].
Improving overall cognitive performance in stressful environments [2].
Improving quality and quantity of sleep [3].

Phenibut is best known for its anxiolytic and cognitive-enhancing effects, including its ability to boost GABA and dopamine levels in the brain.

Research shows dopamine and GABA are powerful neurotransmitters which decrease anxiety and improve overall mood in humans, which explains Phenibuts powerful benefits [4]!

So how does Phenibut work?

Phenibut is technically a GABA-B agonist. This means it selectively binds to and activates GABA-B receptors in the brain [5]. The latest studies show GABA is an inhibitory neurotransmitter which promotes relaxation and a sense of calm in users [6].

Research also shows that Phenibut can boost overall brain dopamine levels, a powerful neurotransmitter which elevates mood, focus, and concentration.

It’s rare to come across a nootropic that boosts both dopamine and GABA simultaneously, which explains the large amount of interest in Phenibut amongst researchers.

Understanding the Mechanism of Action of Phenibut

Phenibut is able to exert its powerful effects as a nootropic by increasing dopamine and GABA levels in the brain.

From there, these powerful neurotransmitters provide numerous physiological benefits including decreased perception of stress, improved focus and cognitive performance, and more.

Here’s a closer look at how Phenibut is able to achieve these outcomes:

GABA receptor modulation: Phenibut is a structural analogue of GABA, an inhibitory neurotransmitter in the brain. Because of this, it selectively binds to GABA receptors in the brain and modulates their activity [7].
GABA-B receptors: Phenibut’s primary target is the GABA-B receptor, which is a metabotropic receptor that regulates the activity of ion channels in neurons [8].
Inhibitory effects: When Phenibut binds to GABA-B receptors, it activates potassium channels and inhibits calcium channels. This ultimately leads to a reduction in neuronal excitability and increased inhibitory tone in the brain [9].
Neurotransmitter modulation: In addition to its effects on GABA receptors, phenibut has been shown to modulate the activity of other neurotransmitter systems, including dopamine and noradrenaline [10].

Overall, Phenibut’s unique ability to boost both GABA and Dopamine neurotransmitters in the brain is responsible for its powerful cognitive-enhancing and mood-elevating effects.

Phenibut Benefits

Phenibut has been successfully studied since the 1960s in the former Soviet Union, and researchers are consistently amazed at its wide range of benefits.

It has the unique ability to boost GABA and dopamine levels in the brain, meaning it has numerous benefits and use-cases.

Some of its most powerful benefits include:

Anxiety Reduction: Phenibut is a powerful anxiolytic nootropic, meaning it has the ability to reduce anxiety and perceived stress levels. This makes it a popular choice for users who are suffering from anxiety or chronic stress [11].
Improved Sleep Quality: The neurotransmitter GABA plays a huge role in an individual’s quality and quantity of sleep. By increasing GABA activity and calming the brain, Phenibut is able to improve the user’s quality and quantity of sleep [12].
Enhanced Cognitive Function: Phenibut is known for its powerful cognitive boosting effects. By elevating brain-dopamine levels, Phenibut improves mood, memory, concentration, and focus. This makes it a popular option for students and researchers [13].
Mood Enhancement: It is well documented that Phenibut users report improved baseline mood levels, and even increased sensations of euphoria. It has even been studied as a potential anti-depression medication [14].
Pain Relief: Some studies suggest that Phenibut decreases perceived pain levels in users [15].

Phenibut clearly has many powerful benefits for users and research subjects. However, it’s important to be aware of its potential side effects as well before studying its unique nootropic properties.

Phenibut Side Effects

Phenibut has earned a reputation as one of the safest nootropics available – provided you are taking the recommended dosage of 250 – 1,500 mg per day.

While side effects are relatively rare, there are some that you should be aware of. Some of the most common side effects of Phenibut include:

Dizziness: Some studies suggest users may experience episodes of dizziness while taking Phenibut. This side effect is typically mild and usually goes away on its own.
Nausea: Nausea is another common side effect of Phenibut. It can be alleviated by taking the supplement with food or using a smaller dosage.
Headaches: Headaches are another common side effect of Phenibut. They often occur while taking the nootropic on an empty stomach, so taking it with food or a drink is recommended.
Dependence: Studies show some users are at risk of developing a dependency on Phenibut when using it for prolonged periods of time.
Withdrawal Symptoms: Abruptly stopping Phenibut use can lead to withdrawal symptoms, including anxiety, insomnia, tremors, and hallucinations. Phenibut users are encouraged to gradually decrease or taper off Phenibut use to avoid withdrawal symptoms.

While these side effects are possible, they are relatively rare.

The easiest way to avoid these potential side effects is to start with a small dose of Phenibut, and gradually increase the dose until you find your “sweet spot.”

Phenibut Withdrawal Symptoms

Phenibut is generally considered one of the safest nootropics available today. However, when used at high doses for extended periods of time, some users may be at risk for developing withdrawal symptoms.

Abruptly stopping Phenibut use may result in the following withdrawal symptoms in some individuals:

Anxiety
Insomnia
Tremors
Hallucinations
Agitation
Irritability
Depression
Sweating
Headaches
Nausea

Withdrawal symptoms from Phenibut use varies depending on multiple factors, including genetic predisposition, dosages used, and duration of use.

Fortunately, Phenibut withdrawal symptoms can be minimized or avoided entirely by using low-moderate doses, and cycling off Phenibut for a period of time to re-sensitize your body to its effects.

When using Phenibut with high doses for extended periods of time, it is essential to gradually reduce your dosage to minimize the risk of experiencing withdrawal symptoms.

(Phenibut.com, sponsored) When using Phenibut with high doses for extended periods of time, it is essential to gradually reduce your dosage to minimize the risk of experiencing withdrawal symptoms.

Phenibut Dosage Calculator and Chart

By now you’re probably curious about how much Phenibut to use… The truth is the optimal Phenibut dose depends on numerous factors, including individual response to the nootropic, bodyweight, age, and other factors.

However, it is possible to make some general guidelines for optimal dosing protocols:

Phenibut Dosage Calculator

It is also possible to calculate your optimal Phenibut dosage based on your bodyweight. Researchers have found the following dosage calculator to be particularly helpful for this purpose:

Body weight (in lbs) x 1-3 = Recommended Daily Dosage (in mg)

For example, here are some sample calculations for individuals with different body weights:

150 lbs x 1-3 = 150 - 450 mg per day
200 lbs x 1-3 = 200 - 600 mg per day
250 lbs x 1-3 = 250 - 750 mg per day

We recommend starting with a relatively low dose, and slowly increasing until you find your sweet spot.

It’s important to note that this dosage calculator is just a rough starting point. Individual responses to Phenibut vary widely, so the optimal dose for one person may be significantly higher or lower than that for another.

Phenibut Dosage Recommendations

Here are some general guidelines for optimal Phenibut dosages:

Low Dose: 200 - 500 mg per day
Medium Dose: 500-1,000 mg per day
High Dose: 1,000-1,500 mg per day

It is essential to start with a low dose and gradually increase the dosage as needed. Phenibut should not be taken for more than two weeks continuously.

It is also important to cycle dosage to prevent tolerance and dependence.

Phenibut Review | Does the Nootropic Actually Work?

Research shows that Phenibut is a powerful Nootropic with numerous benefits for improving mood, memory, concentration, and overall cognitive performance. But does it actually work in the real world?

In other words, are users’ real-world experience backing up what researchers are finding in the lab?

The short answer is a YES – Phenibut works extremely well, and is one of the strongest overall nootropics. Let’s take a closer look at our own experience from testing the nootropic, as well as case studies from other individuals.

Our Experience With Phenibut…

We have been using Phenibut for several years, and we must say it is one of our absolute favorite nootropics.

We don’t like to use it all the time, as there is a real risk for developing dependence or withdrawal symptoms. However, when used in moderation Phenibut is an absolute game-changer.

Here are a few of the benefits we personally experienced while using Phenibut:

Decreased Stress – It’s as if our anxiety just disappears while using the nootropic
Enhanced Cognition – Thanks to increased dopamine levels, our cognitive performance including focus, concentration, and short-term memory all improved.
Increase Euphoria – Phenibut is one of those nootropics that just makes you feel euphoric. Even when we are busting out a 6-12 hour day of work, Phenibut helps us actually enjoy the work.

We even noticed other benefits like improved quality and quantity of sleep. Some of our testers experienced jitters while using higher doses, but this was resolved by just adjusting the dose.

Phenibut User Reviews…

Based on the feedback of thousands of real-world Phenibut users, it’s safe to say that other individuals are experiencing many of the same mood-enhancing and cognitive-boosting benefits that we have experienced.

For example, here is one recent review from a verified Phenibut user:

“Have been taking Phenibut for 4 years now. Works great with no side effects. Calms my anxiety, improves my sleep, and provides me with motivation and an out-going personality. Must be taken in small doses (1,000mg or less a day) and never taken more than 2-3 days in a row. I actually take every other day and I would not call it addictive at all.” - Rick B

This kind of feedback is incredibly common from first-time Phenibut users. They are simply blown away by how powerful it is!

Overall, Phenibut works just as well in the real world as it does in research studies. If you are looking for a powerful nootropic with numerous benefits and few side effects, then Phenibut is an excellent choice!

Forms of Phenibut

Before purchasing Phenibut from a high-quality online vendor like Science.bio, it’s important to learn about the different types of Phenibut that are available.

The truth is Phenibut comes in several different forms, including capsules, liquids, powder, and crystals. There are also several different types of Phenibut, including Phenibut HCL and Phenibut FAA.

Let’s start by examining the different types of Phenibut, followed by the different administration forms.

Phenibut Types

There are three main types of Phenibut: Phenibut HCL, Phenibut FAA, and F-Phenibut.

They all have similar properties, but vary significantly in terms of their potency, speed of absorption, and duration of effects.

Phenibut HCL: Phenibut HCL is the most common form of Phenibut. It is a salt-form of Phenibut with hydrochloric acid added. Phenibut HCL is very safe and lasts for about 8 hours in the body, but it requires slightly higher doses to achieve optimal results.
Phenibut FAA: Phenibut FAA is a free amino acid form of Phenibut. It is significantly more potent than traditional Phenibut HCL and absorbs faster, but its effects only last for about 5 hours. Phenibut FAA is often preferred by people who want the most efficient and effective form of Phenibut.
F-Phenibut: F-Phenibut is a more potent form of Phenibut that has a fluorine atom added to its structure. It is more potent than Phenibut HCL and FAA and has a quicker onset of action. However, it is also associated with more severe side effects and should be used with caution.

Overall, we recommend beginners start with Phenibut HCL. More experienced users can use a more powerful version like F-Phenibut to get maximum results.

Phenibut Forms

Phenibut comes in several different administration forms, each with their own unique advantages and disadvantages.

These forms include:

Capsules: Phenibut capsules are the most popular option. They are pre-measured, so you can make precise changes in your dosing protocols. They are also very convenient, and easy to take.
Liquid: Phenibut liquid is another convenient option for Phenibut administration. All you have to do is mix the liquid solution with water (or another beverage) and drink the solution. Liquid Phenibut is absorbed more quickly than capsules, making it ideal for people who need fast-acting relief from anxiety or stress.
Powder: Phenibut powder is the least expensive form of Phenibut. It’s perfect for advanced users who want 100% control over how much Phenibut they are taking at a time. However, anyone using Phenibut powder must be extremely careful to weigh their doses correctly.
Crystals: Phenibut crystals are the purest form of Phenibut. They are usually dissolved in water before consumption, and are virtually free of all impurities. Phenibut crystals are recommended for anyone looking for the purest, most effective form of Phenibut.

To summarize, Phenibut can be administered in different forms, including capsules, liquid, powder, and crystals. Each form has its advantages and disadvantages.

There are also different types of Phenibut including Phenibut HCL or Phenibut FAA which have slightly different effects in the body.

Users are encouraged to research each form and type of Phenibut to better understand their advantages and disadvantages.

Where To Buy Phenibut Online?

Purchasing from a high-quality online Phenibut vendor is absolutely critical.

After all, there is nothing worse than realizing you tested a low-quality product that is filled with cheap fillers and impurities…

Our team of experts has personally tested and reviewed every major online Phenibut vendor. We believe the best vendor depends on what type of Phenibut you are looking to purchase.

Here are our top recommendations:

Capsules: Liftmode
Liquid: Science.Bio
Powders: Science.bio
Fine Crystals: Lift Mode

Science.bio is our #1 overall choice, but researchers looking to study the effects of Phenibut capsules or fine crystals may prefer ordering from Liftmode or Pure Rawz.

Here is some additional information on each vendor to help you make an informed decision:

1. Science.bio

Science.bio is the #1 online Phenibut vendor for researchers looking to study the effects and benefits of this powerful nootropic product.

The thing that separates Science.bio from other Phenibut vendors is their commitment to quality. They test all of their products using rigorous 3rd-party testing protocols, which ensures you get the highest quality product.

Other benefits of Science.bio include:

Commitment to Quality and Purity: Science.bio has extremely high standards for all their products. All products go through rigorous 3rd-party testing protocols to ensure they are pure and free of contaminants.
Unique Batch Tracking System: Science.bio has systems in place to track each batch of Phenibut that is manufactured. The lot number and information is available for each product, so customers can verify the third-party testing of their product.
Wide Selection of Products: Science.bio offers a wide selection of products, including Phenibut, other nootropics, and other research chemicals.
Fast and Reliable Shipping: Science.bio offers some of the best shipping rates in the world, with free shipping on all orders over $100 and fast domestic and international shipping policies.
Excellent Customer Service: We personally tested science.bio’s customer support, and we were blown away by how helpful we found them. No matter what question you have, science.bio’s team of experts is there to help!

Overall, Science.bio is the clear #1 choice for anyone looking for a high quality online Phenibut vendor. This is especially true if you are interested in Phenibut liquids or powders.

But don’t just take our word for it - here is what real Science.bio customers are saying about this product:

“Highly recommended for reliable research products and exceptionally helpful & prompt customer service. I have been purchasing from Science.bio starting in early August 2020, and I have been satisfied with multiple orders each month since. Consistent quality with a wide variety of safe and secure payment methods to work with!” - VW

With reviews like these, its easy to see why Science.bio is one of the most reputable online Phenibut vendors in the world!

2. Liftmode

Liftmode is one of the premier online Phenibut vendors that offers unmatched quality for Phenibut liquids and powders.

Liftmode specializes in producing high-quality nootropics supplements - including Phenibut.

Here are just a few of the reasons they are one of our preferred vendors:

High-quality Phenibut that is tested for purity and quality
Fast, reliable shipping that is 100% free on orders over $69
Extremely competitive prices on all products, including Phenibut
Great rewards program for repeat customers

Overall, Liftmode is an excellent choice for anyone interested in testing out the powerful effects of Phenibut.

3. Pure Rawz

Pure Rawz is a vendor that specializes in producing premium quality Phenibut powders and fine crystals. They also offer a wide variety of nootropics and other research chemicals, regardless of your individual goals.

One of the things that separates Pure Rawz from other online Phenibut vendors is their commitment to manufacturing the highest quality products.

All of their Phenibut products undergo strict third-party lab testing to ensure purity and potency of their products. They also offer incredibly fast shipping times, competitive pricing, and multiple payment options including credit card, paypal, bitcoin, and Zelle.

(Phenibut.com, sponsored) Phenibut and F-Phenibut are two closely related compounds that have similar, but slightly different effects in the body.

Phenibut vs. F-Phenibut

Phenibut and F-Phenibut are two closely related compounds that have similar, but slightly different effects in the body.

Both of these nootropics help to relieve symptoms of anxiety and improve overall mood. However, there are some key differences in terms of their potency, and how long they remain active in the body.

Here are some of the key differences between Phenibut and F-Phenibut:

Potency: F-Phenibut is more potent than Phenibut, meaning a lower dosage of F-Phenibut is required to achieve maximum benefits.
Onset Time: The effects of F-Phenibut are felt almost immediately, while Phenibut HCL takes a slightly longer time to fully absorb.
Half-life: F-Phenibut has a shorter half-life than Phenibut. F-Phenibut lasts for about 5 hours in the body, while the effects of Phenibut HCL last for approximately 8 hours.
Side Effects: Overall, side effects while using Phenibut HCL are extremely rare, while F-Phenibut is sometimes associated with more severe side effects, including nausea, vomiting, and dizziness.
Addiction Potential: F-Phenibut has a higher potential for addiction and dependence than Phenibut.

To summarize, Phenibut HCL and F-Phenibut are two popular forms of the powerful nootropic Phenibut.

While they have similar overall effects in the body, they differ significantly in terms of their potency, speed of absorption, and half-life in the body.

Is Phenibut Legal?

You may be wondering if Phenibut is actually legal. The truth is the legal status of Phenibut varies from one country to the next.

While some countries like the United States make it legal for individuals to purchase Phenibut without a valid doctor’s prescription, other countries have more restrictive laws governing its use and possession.

Here’s a breakdown of the legal status of Phenibut in several Western countries:

United States: It is 100% legal to use and possess Phenibut in the United States without a valid doctor’s prescription.
Canada: The legal status of Phenibut in Canada is murky. While it is legal to use or possess Phenibut, there are restrictions on how companies can market Phenibut to consumers.
United Kingdom: Phenibut is a prescription-only medicine in the UK, meaning it can only be obtained with a valid prescription from a licensed doctor or physician. healthcare professional.
Australia: It is currently illegal for Australian citizens to purchase or use Phenibut without a valid doctor’s prescription.

Phenibut is definitely one of those “grey-area” nootropics where it is legal in some countries, and illegal in others.

If you are interested in purchasing and using Phenibut, we recommend verifying the legal status of the nootropic in your country.

Is Phenibut Safe?

Phenibut is generally considered a safe nootropic – especially when taken at the recommended dosages. However, like any supplement or medication, Phenibut can cause side effects when used improperly or at excessively high doses.

Here are some key points to consider when evaluating the safety of Phenibut:

Side Effects: Phenibut can cause side effects such as dizziness, nausea, headaches, and fatigue. Fortunately, these side effects are usually mild and go away on their own
Dosage: To reduce the risk of side effects, users are encouraged to start with a relatively small dose of Phenibut of 200 – 300 mg per day, and slowly increase to assess tolerance.
Addiction Potential: Some individuals may be at risk of developing an addiction to Phenibut. To reduce the risk of addiction, users are encouraged to “cycle” Phenibut, with periods where they are not using it.
Duration: The effects of Phenibut tend to last for approximately 5-8 hours, depending on which type of Phenibut you are using.
Interactions: Phenibut may interact with other substances, including alcohol and prescription medications.

Overall, Phenibut is a very safe nootropic when used correctly.

However, users are encouraged to monitor for side effects and adjust their dosage as necessary to minimize their occurrence.